Overcoming the Challenges in Asymmetric Bispecific Antibody Production by Using Quick’n Clean Platform
Gaozhan Zhang, Lupeng Cui, Dawei Zhang, Mengjie Lu, Jiansheng Wu
WuXi Biologics, NO.240 Hedan Road, Pudong New District, Shanghai, China

Bispecific antibody (BsAb) is a large family of molecules designed to recognize two different epitopes or antigens and represents a highly promising class of biotherapeutic modality. Unlike vanilla antibody, great production challenges with respect to the quantity, quality, and stability of bispecific antibodies have hampered their wider clinical application and acceptance. To support our clients and to overcome the challenges associates with BsAb production, WuXi Biologics has established one HTP BsAb production platform “Quick’n Clean”
This scientific poster was originally presented during the PEGS Boston 2023 conference