Payloads and Linkers
Below is short list of common payloads and linkers available for immediate purchase (GMP or non-GMP). For the full list of “ready-to-conjugate” chemical entities see the table at the bottom of this webpage.
- Payloads: MMAE*, VC-MMAE*, MMAF, MC-MMAF*, DM1, DM4, SN38, Exatecan mesylate (DX-895 1f)*, PNU159682, PBD, and Teserine.
- Linkers: MC-VC-PAB-PNP, Glu-VC-PAB, NHS-Glu-VC- PAB, Azido-Glu-VC-PAB, Hydrazone (acid sensitive), Disulfide (glutathione sensitive), SMCC and Fmoc-VAL- ALA-PAB-PNP
*Drug Master File (DMF) is available with specific regulatory agencies. Please contact us (see submission form on the right) for more information.