Clinical Manufacture

Commercial Manufacture

Drug Product Fill & Finish

Development

Testing

Discovery

Antibody Drug Conjugates

Technologies & Platforms

Our team provides high-throughput screening by ELISA, FACS and other image-based binding methodologies, as well as antibody biochemical characterization to ensure the identification of antibody drug candidates with high potency that are suitable for functional assays and animal studies.

Primary Screening

Throughput: 10,000 – 50,000 samples per assay

  • Binding screen by ELISA (protein-based)
  • Binding screen by FACS (cell-based)
  • Binding screen by Mirrorball (Image-based homogenous assay, protein- or cell-based)

Secondary Screening

Throughput: 1,000 – 3,000 samples per assay

  • Orthologue (cross-species) and homologue (cross-family) screen
  • Quantitation ELISA / FACS
  • Competition ELISA

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MAb Characterization

We offer MAb characterization services to better understand the identity, titer/concentration, purity, structure, conformation, glycan profiles, sequence, aggregation and other post-translational modifications of the molecules.

Throughput: 100 -300 samples per assay

Services include:

  • Antibody isotyping
  • Epitope binning
  • Affinity ranking (Whole IgG, scFv or Fab format)
  • SPR-based affinity measurement
  • Cell surface protein affinity estimation by FACS

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Standalone Services

FACS service

  • High throughput FACS screening
  • High resolution FACS analysis
  • Affinity estimation by FACS Scatchard analysis for cell surface antigen

SPR based biomolecular interaction service

  • Full kinetics analysis (antibody-antigen, receptor-ligand etc.)
  • Antibody affinity ranking (Whole IgG, scFv or Fab format Koff ranking)
  • Epitope binning
  • Competitive binding assay

Luminex service

  • Antibody isotyping
  • Multiplex assay for detecting extracellular and intracellular analytes (up to 50 analyates per well)

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