Service Item |
Description |
Duration |
Request A Quote |
DSF for Tm, one (1) molecule |
1. Sample requirements: protein samples amount >25 ug; concentration >0.1 mg/mL
2. Deliverables: protein melting temperature Tm
|
2 weeks |
|
AC-SINS for self-association, one (1) molecule |
1. Sample requirements: antibody samples amount >20 μg; concentration >0.5 mg/mL
2. Deliverables: wavelength shift compared to blank AuNP; self-association score
|
2 weeks |
HIC HPLC for self-association, one (1) molecule |
1. Sample requirement: antibody samples amount >50 μg; concentration >0.5 mg/mL
2. Deliverables: hydrophobicity of the sample and the correlation with AC-SINS data (if applicable)
|
2 weeks |
Particle size by DLS (DLS-Radius) |
1. Sample requirement: antibody samples purity >95%, concentration >1.5 mg/mL, 100 μL
2. Deliverables: particle size distribution
|
2 weeks |
Solubility check and predication (DLS-kD & Appearance inspection) |
1. Sample requirement: antibody samples purity >95%, amount >4 mg; concentration >0.5 mg/mL
2. Deliverables: kD
|
2 weeks |
Optional: High concentration study with viscosity, one (1) molecule
Note: least 100 mg materials will be needed.
|
1. Sample requirement: antibody samples volume >50 μL; concentration based on needs
2. Deliverables: viscosity at designated concentrations
|
2 weeks |
Baculovirus ELISA, one (1) molecule |
1. Sample requirement: antibody samples amount >250 μg; concentration >0.5 mg/mL
2. Deliverables: titration curve and baculovirus binding score
|
2 weeks |
DNA ELISA, one (1) molecule |
1. Sample requirement: antibody samples amount >250 μg; concentration >0.5 mg/mL
2. Deliverables: titration curve and DNA binding score
|
2 weeks |
Insulin ELISA, one (1) molecule |
1. Sample requirement: antibody samples amount >250 μg; concentration >0.5 mg/mL
2. Deliverables: titration curve and insulin binding score
|
2 weeks |
FcRn binding assay, one (1) molecule |
1. Sample requirement: antibody samples amount >20 μg; concentration >0.5 mg/mL
2. Deliverables: association profile at pH 6.0, dissociation profile at pH 6.0 and pH 7.4; KD fitting for pH 6.0 (if applicable)
|
2 weeks |
FcγRI/FcγRII/FcγRIII binding assay one (1) molecule |
1. Sample requirement: antibody samples amount >20 μg; concentration >0.5 mg/mL
2. Deliverables: binding profile and constant
|
2 weeks |
Serum cleavage assay, one (1) molecule |
1. Sample requirement: antibody samples amount >100 μg; concentration >0.5 mg/mL
2. Deliverables: protein cleavage percentage and/or cleavage sites
|
2 weeks |