WuXi Biologics
Offering End-to-End Solutions
At WuXi XDC, the conjugation manufacturing process for ADC/bioconjugate drug substance starts with payload-linker dispensing and consists of the conjugation reaction, purification and bulk filling.
There are two dispensing cabinets for weighing and dissolving highly-potent compounds, which include a stainless steel negative pressure isolator and a single-use plastic isolator.
See the table below for manufacturing capacities.
|
mAb
|
Payload-Linker
|
ADC
|
Lab scale
|
√
|
√
|
√
|
Non-GMP pilot scale
|
√
|
√
|
√
|
cGMP manufacturing
|
> 2 kg
|
> 5 kg
|
Up to 5 kg
|
White paper: The Watershed Moment for ADCs has Arrived
Podcast: Antibody Drug Conjugate (ADC) Development And Manufacturing Challenges And Solutions
Webinar: Antibody Drug Conjugates (ADC) drug development and manufacturing trends, challenges and solutions