Interferometry-Based Measurement of Silicone Oil Thickness in both Empty and Filled Syringes
Chengyu Liu, Jiamin Li, Xiaozhi Lv, Heming Xu, Yunyun Wang, Zhixin Zhao, Shuying Ji, Guisheng Zhuang, Quanmin Chen, Jeremy Guo
Silicone oil serves as a lubricant in prefilled syringes (PFSs) and its quantity significantly impacts the functionality of the syringes. Consequently, monitoring silicone oil layer thickness and distribution is crucial for understanding the impact on the functionality and/or stability of a combo product. In this poster, we detail our comprehensive approach for measuring silicone oil thickness in both empty and filled syringes.
This scientific poster was originally presented during the 2023 PDA Universe of Pre-Filled Syringes and Injection Devices Conference.