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Offering End-to-End Solutions
WuXi Biologics can provide a variety of high throughput, high sensitivity and high content in vitro assays.
Affinity by SPR (Surface Plasmon Resonance)
Bispecific antibody simultaneous binding
Related SPR service
WuXi Biologics offers a variety of animal models to support biologics efficacy study and IND filing.
Mouse, rat, cynomolgus monkey PK, ADA and exploratory toxicology studies.
WuXi Biologics offers developability studies at the discovery stage to support lead selection and reduce CMC development risk. These early-stage developability studies need just 5-10 mg samples and the studies take only 2-3 weeks to perform.
|Deamidation/ isomerization stress test||UV, SEC-HPLC, cIEF, SPR for potency||1 week|
|Oxidation stress test||UV, SEC-HPLC, HIC, SPR for potency||1 week|
|Melting temperature (Tm)||DSF or DCS||3 days|
|Colloidal stability kD – (mL/g)||DLS||1 week|
|Stressed thermal stability||40 ºC||1-2 week|
|Freeze/thaw stability||5x, -80 ºC /RT UV, SEC-HPLC, cIEF||