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WuXi Biologics
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Antibody Production Services
At Protein Sciences, we pride ourselves on being a comprehensive solution provider that unites our biologics development expertise with cutting-edge antibody production services. Our team brings a wealth of experience, that empowers us to offer a diverse range of high-quality antibody production services and avoid pitfalls in the antibody drug development process.
Key Features of our Antibody Production Services:
- High Titer Expression: Harnessing the latest advancements in biotechnology, we excel in achieving high titer expression of antibodies, maximizing the yield for your antibodies.
- Premium Quality: Our team of experts are comprised of skilled scientists who are well-versed in both expression and purification of antibodies. With our rigorous quality control measures throughout the antibody production process, we ensure consistent and reliable results.
- Speedy Turnaround: Time is of the essence in research. With our high titer expression platform and optimized operation processes, we can deliver your antibodies in just 3 weeks.
- Cost-effective Solutions: Empowered by our high titer expression platform, we achieve the same amount of antibodies with a much smaller culture volume and a shorter production time, which translates to the low cost to our customers.
Antibody Production Services (by Antibody Type)
Monoclonal Antibody Production
Harness our high-titer expression systems for high-purity, low-endotoxin mAb production in a fast and cost-effective way, from 1 mL small-scale high-throughput production to 100 L large-scale production.
Bispecific Antibody Production
Utilize our expertise in bsAb production, from the HTP generation and identification of the optimal bispecific pairings to the delivery of high-purity, gram-level bsAbs, suitable for both in vitro and in vivo studies.
Fab Fragments, VHH, scFv
Leverage our WuXian™ Transient (CHO & HEK293), WuXian™ Express (CHO Stable Pool), and E. coli expression systems for high-titer expression of quality antibody fragments, including Fab, VHH, scFv, and sdAb (nanobody).
Extensive Experience in the Production of Diverse Antibodies
From traditional monoclonal antibodies to innovative bispecific antibodies and various antibody fragments such as Fab fragments, VHH, and scFv, we synergize our drug-making knowledge with antibody production to deliver unparalleled results, ensuring that our clients receive top-tiered antibodies to drive groundbreaking research and therapeutic advancements.
Our Featured Antibody Production Services
HTP Ab production in 96/24 deep well plate, resulting in a daily throughput of 1000x Ab production at 100 ug-1.5 mg each, suitable for in vitro assays.
1-100 mg low endotoxin (<0.5 EU/mg) and low aggregate (>95% monomer) Ab production in just 3 weeks, suitable for both in vitro and in vivo studies.
HTP small-scale bsAb production to unlock the optimal pairings of bsAB in a fast and cost-effective way.
One-stop solution for evaluating the suitability of antibodies as potential drug using <1mg Ab, enabling early-stage screen to eliminate undruggable targets.
Gold standard for large scale bsAb production. With unparalleled expertise and extensive purification experience with different BsAb formats, we ensure the precise form of bispecific antibodies in every final product, delivering exceptional quality and unmatched reliability.
Premium-quality monoclonal antibodies ranging from 1-100 grams in 3-4 weeks. Our platform synergizes ultra-high titer transient expression with flexible purification processes.
Frequently Asked Questions for Antibody Production
Q: Which cell lines are used by WuXi Biologics for antibody production?
A: We primarily use CHO cells for antibody production. We have made significant investments in optimizing our cell engineering and cell growth processes to achieve high titer expression of antibodies in the CHO cells, enhancing the antibody production efficiency.
Q: How long does it typically take to produce antibodies with WuXi Biologics?
A: The antibody production timeline varies depending on several factors, including the type of antibody, the scale of production, and specific client requirements. Using our HTP platforms and high titer expression CHO cells, the timeline could be as fast as 2 weeks, with a daily throughput of 1000+ molecules.
Q: What makes WuXi Biologics’ antibody production unique?
A: Our unique advantage lies in providing valuable insights and guidance to customers throughout the entire antibody drug development process, enabling them to navigate around common pitfalls and overcome challenges effectively. This comprehensive end-to-end viewpoint and approach ensures a seamless and speedy journey from concept to market, making us a trusted and reliable partner for customers in need of antibody production services.