Antibody Drug Conjugates (ADCs)
WuXi Biologics offers comprehensive, one-stop in vitro and in vivo characterization services to assist our clients and enable them to discover the ideal ADC candidate to move into CMC development and on to clinical trials.
ADC In Vitro Characterization Platform
Comprehensive biologics screening and characterization throughout the lead drug candidate selection process is provided. We also offer assay development services as required for your specific project needs. ADC in vitro characterization services and methods include:
Antigen-antibody binding methods
Internalization analysis
- pHrodo
- Acid quench
- Co-localization
- Time-course
Other critical in vitro characterization evaluations
- High-throughput and quick cytotoxicity assessment
- Bystander killing
- Free-payload release and drug-to-antibody ratio (DAR) stability for serum or plasma samples
For more information including case studies illustrating our in vitro characterization capabilities for ADCs, download this informative flyer: https://www.wuxibiologics.com/adc-characterization-services-info/